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Category Archives: Medications

COX-2 inhibitor

Cox-2 Inhibitor

(ĐTĐ) – COX-2 selective inhibitor is a form of Non-steroidal anti-inflammatory drug (NSAID) that directly targets COX-2, an enzyme responsible for inflammation and pain.   Selectivity for COX-2 reduces the risk of peptic ulceration, and is the main feature of celecoxib, rofecoxib and other members of this drug class. COX-2 selectivity does not seem to […]

Non-steroidal anti-inflammatory drug

Non-steroidal Anti-inflammatory Drug

(ĐTĐ) – Nonsteroidal anti-inflammatory drugs, usually abbreviated to NSAIDs or NAIDs, are drugs with analgesic and antipyretic (fever-reducing) effects and which have, in higher doses, anti-inflammatory effects (reducing inflammation). The term "nonsteroidal" is used to distinguish these drugs from steroids, which (among a broad range of other effects) have a similar eicosanoid-depressing, anti-inflammatory action. As […]

Analgesic

Analgesic

An analgesic (also known as a painkiller) is any member of the group of drugs used to relieve pain (achieve analgesia). The word analgesic derives from Greek an- (“without”) and algos (“pain”). Analgesic drugs act in various ways on the peripheral and central nervous systems; they include paracetamol (para-acetylaminophenol, also known in the US as […]

The journey from pain relief to addiction

(ĐTĐ) – New research reveals that Australians are consuming more prescription drugs than ever before. Among the most dangerous and addictive families of drugs are opioids, strong pain killers used for people with injuries and drug dependencies. Increasingly the drugs seem to be being abused, as Shevonne Hunt writes.   Simon Millington did not have […]

Ask the Pharmacist: What Will Hydrocodone Rescheduling Mean for Pharmacies?

(ĐTĐ) – On October 6th, all hydrocodone combination products will be reclassified in the U.S. as a Schedule II drugs under the Controlled Substances Act. For all of those involved in dealing with chronic pain — prescribers, pharmacists, and patients — the impact could be more than minimal.   For the Pharmacist and his/her staff […]

New Drugs May Help Prevent Migraines

(ĐTĐ) – Two experimental drugs may help prevent migraines in people who suffer multiple attacks a month, according to preliminary findings from a pair of clinical trials.   The drugs, one given by IV and one by injection, are part of a new approach to preventing migraine headaches. They are "monoclonal antibodies" that target a […]

Are Medication Overuse Headaches Associated With NSAIDs?

(ĐTĐ) – Question: Are medication overuse headaches associated with use of nonsteroidal anti-inflammatory drugs?   Response from Jenny A. Van Amburgh, PharmD, CDE (Assistant Dean of Academic Affairs; Associate Clinical Professor, School of Pharmacy, Northeastern University; Director, Clinical Pharmacy Team Director, Residency Program, Harbor Health Services, Inc., Boston, Massachusetts): Medication overuse headache (MOH), previously called […]

Greater Use of Meds to Halt Opioid Overdose Epidemic Urged

(ĐTĐ) – US addiction experts are urging expanded use of medications to combat the "opioid overdose epidemic" plaguing the country.   In a commentary published April 23 (2014) in the New England Journal of Medicine, National Institute of Drug Abuse (NIDA) director Nora Volkow, MD, and colleagues from other US Department of Health and Human […]

NSAIDs Double Bleeding Risk With Anticoagulants for DVT/PE

(ĐTĐ) – Patients receiving an anticoagulant for deep vein thrombosis (DVT) or pulmonary embolism (PE) who take a nonsteroidal anti-inflammatory drug (NSAID) or aspirin for pain or headache, even for a few days, are at heightened risk for a major bleed, according to a new study published online April 14, 2014 in JAMA Internal Medicine […]

Amitriptyline for Treating Fibromyalgia: A Help or Hindrance?

(ĐTĐ) – There are numerous treatments available for the symptoms associated with fibromyalgia. Fibromyalgia is classified as a disorder of pain processing due to abnormalities in the ways in which pain signals are processed in the central nervous system.   Patients suffering from fibromyalgia often complain of depression, insomnia,irritable bowel syndrome, painful and tender points […]

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